A retrospective comparative exploratory study on two Methylentetrahydrofolate Reductase (MTHFR) polymorphisms in esophagogastric cancer: the A1298C MTHFR polymorphism is an independent prognostic factor only in neoadjuvantly treated gastric cancer patients

BACKGROUND: Methylentetrahydrofolate reductase (MTHFR) plays a major role in folate metabolism and consequently could be an important factor for the efficacy of a treatment with 5-fluorouracil. Our aim was to evaluate the prognostic and predictive value of two well characterized constitutional MTHFR...

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Detalhes bibliográficos
Main Authors: Blank, Susanne, Rachakonda, Sivaramakrishna, Keller, Gisela, Weichert, Wilko, Lordick, Florian, Langer, Rupert, Springfeld, Christoph, Bruckner, Thomas, Becker, Karen, Kumar, Rajiv, Ott, Katja
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2014
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3922603/
https://ncbi.nlm.nih.gov/pubmed/24490800
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2407-14-58
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