Interleukin-6 is required for cell cycle arrest and activation of DNA repair enzymes after partial hepatectomy in mice

BACKGROUND: Interleukin-6 (IL-6) has been shown to be vital for liver regeneration, however the specific mechanisms and factors involved remain incompletely defined. The present study aimed to investigate whether IL-6 exerts its protective effects via arresting the cell cycle allowing base excision...

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Main Authors: Tachibana, Shingo, Zhang, Xiuying, Ito, Kazushige, Ota, Yoshihiro, Cameron, Andrew M, Williams, George Melville, Sun, Zhaoli
Formato: Artigo
Idioma:Inglês
Publicado: BioMed Central 2014
Assuntos:
Research
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC3922598/
https://ncbi.nlm.nih.gov/pubmed/24484634
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/2045-3701-4-6
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