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The retrovirus pol gene encodes a product required for DNA integration: identification of a retrovirus int locus.

We mutagenized cloned spleen necrosis virus DNA to identify a region of the retrovirus genome encoding a polypeptide required for integration of viral DNA. Five plasmids bearing different lesions in the 3' end of the pol gene were examined for the ability to integrate or replicate following transfec...

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Pubblicato in:Proc Natl Acad Sci U S A
Autori principali: Panganiban, A T, Temin, H M
Natura: Artigo
Lingua:Inglês
Pubblicazione: National Academy of Sciences 1984
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Accesso online:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC392257/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/6083562/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.81.24.7885
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