Age-dependent defective TGF-beta1 signaling in patients undergoing coronary artery bypass grafting

BACKGROUND: Transforming growth factor beta (TGF-β1) is a pleiotropic cytokine, which is deregulated in atherosclerosis; however the role of age in this process is unknown. We aimed to assess whether TGF-β1 signaling is affected by age. METHODS: Vascular smooth muscle cells (VSMC) were obtained from...

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Detalhes bibliográficos
Main Authors: Redondo, Santiago, Navarro-Dorado, Jorge, Ramajo, Marta, Medina, Úrsula, Molina-Sanchez, Pedro, Garces, Zaady, García-Alonso, Mauricio, Reguillo, Fernando, Rodriguez, Enrique, Andres, Vicente, Tejerina, Teresa
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2014
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3922540/
https://ncbi.nlm.nih.gov/pubmed/24495866
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1749-8090-9-24
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