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Leptin and Leptin-Related Gene Polymorphisms, Obesity, and Influenza A/H1N1 Vaccine–Induced Immune Responses in Older Individuals

Obesity is a risk factor for complicated influenza A/H1N1 disease and poor vaccine immunogenicity. Leptin, an adipocyte-derived hormone/cytokine, has many immune regulatory functions and therefore could explain susceptibility to infections and poor vaccine outcomes. We recruited 159 healthy adults (...

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Bibliografiske detaljer
Main Authors: Ovsyannikova, Inna G., White, Sarah J., Larrabee, Beth R., Grill, Diane E., Jacobson, Robert M., Poland, Gregory A.
Format: Artigo
Sprog:Inglês
Udgivet: 2013
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3922536/
https://ncbi.nlm.nih.gov/pubmed/24360890
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.vaccine.2013.12.009
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