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The rat extracellular superoxide dismutase dimer is converted to a tetramer by the exchange of a single amino acid.

Extracellular superoxide dismutase (EC-SOD) is a secreted Cu and Zn-containing glycoprotein. While EC-SOD from most mammals is tetrameric and has a high affinity for heparin and heparan sulfate, rat EC-SOD has a low affinity for heparin, does not bind to heparan sulfate in vivo, and is apparently di...

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Veröffentlicht in:Proc Natl Acad Sci U S A
Hauptverfasser: Carlsson, L M, Marklund, S L, Edlund, T
Format: Artigo
Sprache:Inglês
Veröffentlicht: National Academy of Sciences 1996
Schlagworte:
Online-Zugang:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC39225/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/8643556/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.93.11.5219
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