The rat extracellular superoxide dismutase dimer is converted to a tetramer by the exchange of a single amino acid.
Extracellular superoxide dismutase (EC-SOD) is a secreted Cu and Zn-containing glycoprotein. While EC-SOD from most mammals is tetrameric and has a high affinity for heparin and heparan sulfate, rat EC-SOD has a low affinity for heparin, does not bind to heparan sulfate in vivo, and is apparently di...
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| Veröffentlicht in: | Proc Natl Acad Sci U S A |
|---|---|
| Hauptverfasser: | , , |
| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
National Academy of Sciences
1996
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| Schlagworte: | |
| Online-Zugang: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC39225/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/8643556/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.93.11.5219 |
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