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DNA damage related to increased hydrogen peroxide generation by hypolipidemic drug-induced liver peroxisomes.

Several hypolipidemic drugs and certain industrial plasticizers induce proliferation of peroxisomes, enhance the activity of peroxisome-associated beta-oxidation of fatty acids, and produce hepatocellular carcinomas in the livers of rodents. Because these chemicals themselves are not mutagens and do...

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Bibliografski detalji
Glavni autori: Fahl, W E, Lalwani, N D, Watanabe, T, Goel, S K, Reddy, J K
Format: Artigo
Jezik:Inglês
Izdano: 1984
Teme:
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC392245/
https://ncbi.nlm.nih.gov/pubmed/6096860
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