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Synthesis in animal cells of hepatitis B surface antigen particles carrying a receptor for polymerized human serum albumin.

A recombinant plasmid (pSVS dhfr) encoding the pre-S region and the S gene of human hepatitis B virus (HBV) and murine dihydrofolate reductase (DHFR) cDNA has been used for the transfection of Chinese hamster ovary (CHO) DHFR- cells. Selection of clones resistant to methotrexate has permitted amplif...

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Detalles Bibliográficos
Publicado en:Proc Natl Acad Sci U S A
Principais autores: Michel, M L, Pontisso, P, Sobczak, E, Malpièce, Y, Streeck, R E, Tiollais, P
Formato: Artigo
Idioma:Inglês
Publicado: National Academy of Sciences 1984
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Acceso en liña:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC392221/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/6096851/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.81.24.7708
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