Synthesis in animal cells of hepatitis B surface antigen particles carrying a receptor for polymerized human serum albumin.

A recombinant plasmid (pSVS dhfr) encoding the pre-S region and the S gene of human hepatitis B virus (HBV) and murine dihydrofolate reductase (DHFR) cDNA has been used for the transfection of Chinese hamster ovary (CHO) DHFR- cells. Selection of clones resistant to methotrexate has permitted amplif...

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Bibliographic Details
Main Authors: Michel, M L, Pontisso, P, Sobczak, E, Malpièce, Y, Streeck, R E, Tiollais, P
Format: Artigo
Language:Inglês
Published: 1984
Subjects:
Research Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC392221/
https://ncbi.nlm.nih.gov/pubmed/6096851
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