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Resonance Raman spectroscopy reveals that substrate structure selectively impacts the heme-bound diatomic ligands of CYP17
An important function of steroidogenic cytochromes P450 is the transformation of cholesterol to produce androgens, estrogens, and the cortico-steroids. The activities of cytochrome P450c17 (CYP17) are essential in sex hormone biosynthesis, with severe developmental defects being a consequence of def...
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| Main Authors: | , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2013
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3922198/ https://ncbi.nlm.nih.gov/pubmed/24328388 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/bi4014424 |
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