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Adaptation of leukemia cells to hypoxic condition through switching the energy metabolism or avoiding the oxidative stress

BACKGROUND: Like normal hematopoietic stem cells, leukemia cells proliferate in bone marrow, where oxygen supply is limited. However, the growth and energy metabolism of leukemia cells under hypoxia have not been well understood. Although it has been known that reactive oxygen species (ROS) is gener...

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Hlavní autoři: Goto, Mineaki, Miwa, Hiroshi, Suganuma, Kazuto, Tsunekawa-Imai, Norikazu, Shikami, Masato, Mizutani, Motonori, Mizuno, Shohei, Hanamura, Ichiro, Nitta, Masakazu
Médium: Artigo
Jazyk:Inglês
Vydáno: BioMed Central 2014
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3922169/
https://ncbi.nlm.nih.gov/pubmed/24506813
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2407-14-76
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