Leptin gene promoter DNA methylation in WNIN obese mutant rats

BACKGROUND: Obesity has become an epidemic in worldwide population. Leptin gene defect could be one of the causes for obesity. Two mutant obese rats WNIN/Ob and WNIN/GROb, isolated at National Centre for Laboratory Animal Sciences (NCLAS), Hyderabad, India, were found to be leptin resistant. The pre...

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Detalhes bibliográficos
Main Authors: Kalashikam, Rajender Rao, Inagadapa, Padmavathi JN, Thomas, Anju Elizabeth, Jeyapal, Sugeetha, Giridharan, Nappan Veettil, Raghunath, Manchala
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2014
Assuntos:
Research
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3922147/
https://ncbi.nlm.nih.gov/pubmed/24495350
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1476-511X-13-25
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