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Insight Concerning the Mechanism of Therapeutic Ultrasound Facilitating Gene Delivery: Increasing Cell Membrane Permeability or Interfering with Intracellular Pathways?
Nonviral gene delivery methods encounter major barriers in plasmid DNA (pDNA) trafficking toward the nucleus. The present study aims to understand the role and contribution of therapeutic ultrasound (TUS), if any, in pDNA trafficking in primary cells such as fibroblasts and cell lines (e.g., baby ha...
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| Main Authors: | , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Mary Ann Liebert, Inc.
2014
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3922141/ https://ncbi.nlm.nih.gov/pubmed/24251908 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1089/hum.2013.140 |
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