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Antisense Mediated Splicing Modulation For Inherited Metabolic Diseases: Challenges for Delivery

In the past few years, research in targeted mutation therapies has experienced significant advances, especially in the field of rare diseases. In particular, the efficacy of antisense therapy for suppression of normal, pathogenic, or cryptic splice sites has been demonstrated in cellular and animal...

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Detalhes bibliográficos
Main Authors: Pérez, Belen, Vilageliu, Lluisa, Grinberg, Daniel, Desviat, Lourdes R.
Formato: Artigo
Idioma:Inglês
Publicado em: Mary Ann Liebert, Inc. 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3922136/
https://ncbi.nlm.nih.gov/pubmed/24506780
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1089/nat.2013.0453
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