Anti-idiotypic antibodies reduce efficacy of the attenuated vaccine against highly pathogenic PRRSV challenge

BACKGROUND: The inability of current vaccines to provide effective protection against porcine reproductive and respiratory syndrome virus (PRRSV) infection is not fully understood. One of the reasons might be the presence of anti-idiotypic antibodies (Ab2s) to the envelope glycoprotein GP5 induced b...

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Autors principals: Yu, Ying, Cai, Xuehui, Wang, Gang, Kong, Ning, Liu, Yonggang, Xiao, Yihong, Zhang, Chong, Mu, Yang, Xiao, Shuqi, Zhao, Qin, Wang, Chengbao, Zhang, Gaiping, Hiscox, Julian A, Zhou, En-Min
Format: Artigo
Idioma:Inglês
Publicat: BioMed Central 2014
Matèries:
Research Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3921987/
https://ncbi.nlm.nih.gov/pubmed/24507659
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1746-6148-10-39
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