Anti-idiotypic antibodies reduce efficacy of the attenuated vaccine against highly pathogenic PRRSV challenge

BACKGROUND: The inability of current vaccines to provide effective protection against porcine reproductive and respiratory syndrome virus (PRRSV) infection is not fully understood. One of the reasons might be the presence of anti-idiotypic antibodies (Ab2s) to the envelope glycoprotein GP5 induced b...

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Hlavní autoři: Yu, Ying, Cai, Xuehui, Wang, Gang, Kong, Ning, Liu, Yonggang, Xiao, Yihong, Zhang, Chong, Mu, Yang, Xiao, Shuqi, Zhao, Qin, Wang, Chengbao, Zhang, Gaiping, Hiscox, Julian A, Zhou, En-Min
Médium: Artigo
Jazyk:Inglês
Vydáno: BioMed Central 2014
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Research Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3921987/
https://ncbi.nlm.nih.gov/pubmed/24507659
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1746-6148-10-39
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