Regulation of adipose oestrogen output by mechanical stress

Adipose stromal cells are the primary source of local estrogens in adipose tissue, aberrant production of which promotes oestrogen receptor-positive breast cancer. Here we show that extracellular matrix compliance and cell contractility are two opposing determinants for oestrogen output of adipose s...

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Main Authors: Ghosh, Sagar, Ashcraft, Keith, Jahid, Md Jamiul, April, Craig, Ghajar, Cyrus M., Ruan, Jianhua, Wang, Howard, Foster, Megan, Hughes, Daniel C., Ramirez, Amelie G., Huang, Tim, Fan, Jian-Bing, Hu, Yanfen, Li, Rong
Format: Artigo
Jezik:Inglês
Izdano: 2013
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Article
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC3921626/
https://ncbi.nlm.nih.gov/pubmed/23652009
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ncomms2794
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