Phylogenetic distinction of iNOS and IDO function in mesenchymal stem cell-mediated immunosuppression in mammalian species

Mammalian mesenchymal stem cells (MSCs) have been shown to be strongly immunosuppressive in both animal disease models and human clinical trials. We have reported that the key molecule mediating immunosuppression by MSCs is species dependent: indoleamine 2,3-dioxygenase (IDO) in human and inducible...

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Autors principals: Su, J, Chen, X, Huang, Y, Li, W, Li, J, Cao, K, Cao, G, Zhang, L, Li, F, Roberts, A I, Kang, H, Yu, P, Ren, G, Ji, W, Wang, Y, Shi, Y
Format: Artigo
Idioma:Inglês
Publicat: Nature Publishing Group 2014
Matèries:
Original Paper
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3921585/
https://ncbi.nlm.nih.gov/pubmed/24162664
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/cdd.2013.149
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