Phylogenetic distinction of iNOS and IDO function in mesenchymal stem cell-mediated immunosuppression in mammalian species

Mammalian mesenchymal stem cells (MSCs) have been shown to be strongly immunosuppressive in both animal disease models and human clinical trials. We have reported that the key molecule mediating immunosuppression by MSCs is species dependent: indoleamine 2,3-dioxygenase (IDO) in human and inducible...

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Bibliografiska uppgifter
Huvudupphovsmän: Su, J, Chen, X, Huang, Y, Li, W, Li, J, Cao, K, Cao, G, Zhang, L, Li, F, Roberts, A I, Kang, H, Yu, P, Ren, G, Ji, W, Wang, Y, Shi, Y
Materialtyp: Artigo
Språk:Inglês
Publicerad: Nature Publishing Group 2014
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Original Paper
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC3921585/
https://ncbi.nlm.nih.gov/pubmed/24162664
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/cdd.2013.149
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