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Bortezomib effect on E2F and cyclin family members in human hepatocellular carcinoma cell lines

AIM: To evaluate the effects of the proteasome inhibitor bortezomib (BZB) on E2Fs and related genes in hepatocellular carcinoma (HCC) cells. METHODS: The mRNA levels of the E2F family members (pro-proliferative: E2F1-3 and anti-proliferative: E2F4-8) and of their related genes cyclins and cyclin-dep...

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Detalhes bibliográficos
Main Authors: Baiz, Daniele, Dapas, Barbara, Farra, Rossella, Scaggiante, Bruna, Pozzato, Gabriele, Zanconati, Fabrizio, Fiotti, Nicola, Consoloni, Lara, Chiaretti, Sara, Grassi, Gabriele
Formato: Artigo
Idioma:Inglês
Publicado em: Baishideng Publishing Group Co., Limited 2014
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3921488/
https://ncbi.nlm.nih.gov/pubmed/24574752
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3748/wjg.v20.i3.795
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