CX3CL1 (fractalkine) and TNFα production by perfused human placental lobules under normoxic and hypoxic conditions in vitro: the importance of CX3CR1 signaling

OBJECTIVE: Inflammation and hypoxia activate the fractalkine (CX3CL1) receptor (CX3CR1)-related signaling pathway. Tumor necrosis factor alpha (TNFα) induces CX3CL1, influencing a mechanism of CX3CL1 autoregulation by CX3CR1 expression. We compared spontaneous and lipopolysaccharide (LPS)-induced CX...

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Autors principals: Szukiewicz, Dariusz, Kochanowski, Jan, Mittal, Tarun Kumar, Pyzlak, Michal, Szewczyk, Grzegorz, Cendrowski, Krzysztof
Format: Artigo
Idioma:Inglês
Publicat: Springer Basel 2013
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Original Research Paper
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3921448/
https://ncbi.nlm.nih.gov/pubmed/24270813
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00011-013-0687-z
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