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Sleep and the Price of Plasticity: From Synaptic and Cellular Homeostasis to Memory Consolidation and Integration

Sleep is universal, tightly regulated, and its loss impairs cognition. But why does the brain need to disconnect from the environment for hours every day? The synaptic homeostasis hypothesis (SHY) proposes that sleep is the price the brain pays for plasticity. During a waking episode, learning stati...

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Detalhes bibliográficos
Main Authors: Tononi, Giulio, Cirelli, Chiara
Formato: Artigo
Idioma:Inglês
Publicado em: 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3921176/
https://ncbi.nlm.nih.gov/pubmed/24411729
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.neuron.2013.12.025
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