MVA Vectors Expressing Conserved Influenza Proteins Protect Mice against Lethal Challenge with H5N1, H9N2 and H7N1 Viruses

BACKGROUND: The availability of a universal influenza vaccine able to induce broad cross-reactive immune responses against diverse influenza viruses would provide an alternative to currently available strain-specific vaccines. We evaluated the ability of vectors based on modified vaccinia virus Anka...

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Hlavní autoři: Hessel, Annett, Savidis-Dacho, Helga, Coulibaly, Sogue, Portsmouth, Daniel, Kreil, Thomas R., Crowe, Brian A., Schwendinger, Michael G., Pilz, Andreas, Barrett, P. Noel, Falkner, Falko G., Schäfer, Birgit
Médium: Artigo
Jazyk:Inglês
Vydáno: Public Library of Science 2014
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Research Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3921149/
https://ncbi.nlm.nih.gov/pubmed/24523886
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0088340
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