Validation of In Vivo MRI Blood-Brain Barrier Permeability Measurements by Comparison with Gold Standard Histology

BACKGROUND AND PURPOSE: To validate the blood-brain barrier permeability measurements extracted from perfusion-weighted MRI through a relatively simple and frequently applied model, the Patlak model, by comparison with gold standard histology in a rat model of ischemic stroke. METHODS: Eleven sponta...

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Detalhes bibliográficos
Main Authors: Hoffmann, Angelika, Bredno, Jörg, Wendland, Michael F., Derugin, Nikita, Hom, Jason, Schuster, Tibor, Su, Hua, Ohara, Peter T., Young, William L., Wintermark, Max
Formato: Artigo
Idioma:Inglês
Publicado em: 2011
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3921072/
https://ncbi.nlm.nih.gov/pubmed/21636816
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1161/STROKEAHA.110.597997
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