Calumenin-15 facilitates filopodia formation by promoting TGF-β superfamily cytokine GDF-15 transcription

Filopodia, which are actin-rich finger-like membrane protrusions, have an important role in cell migration and tumor metastasis. Here we identify 13 novel calumenin (Calu) isoforms (Calu 3–15) produced by alternative splicing, and find that Calu-15 promotes filopodia formation and cell migration. Ca...

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Detalhes bibliográficos
Main Authors: Feng, H, Chen, L, Wang, Q, Shen, B, Liu, L, Zheng, P, Xu, S, Liu, X, Chen, J, Teng, J
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2013
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Original Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3920949/
https://ncbi.nlm.nih.gov/pubmed/24136234
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/cddis.2013.403
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