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Src42A modulates tumor invasion and cell death via Ben/dUev1a-mediated JNK activation in Drosophila
Loss of the cell polarity gene could cooperate with oncogenic Ras to drive tumor growth and invasion, which critically depends on the c-Jun N-terminal Kinase (JNK) signaling pathway in Drosophila. By performing a genetic screen, we have identified Src42A, the ortholog of mammalian Src, as a key modu...
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| Main Authors: | , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Nature Publishing Group
2013
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3920939/ https://ncbi.nlm.nih.gov/pubmed/24136228 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/cddis.2013.392 |
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