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Modulation of Wolframin Expression in Human Placenta during Pregnancy: Comparison among Physiological and Pathological States

The WFS1 gene, encoding a transmembrane glycoprotein of the endoplasmic reticulum called wolframin, is mutated in Wolfram syndrome, an autosomal recessive disorder defined by the association of diabetes mellitus, optic atrophy, and further organ abnormalities. Disruption of the WFS1 gene in mice cau...

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Bibliografiska uppgifter
Huvudupphovsmän: Lucariello, Angela, Perna, Angelica, Sellitto, Carmine, Baldi, Alfonso, Iannaccone, Alessandro, Cobellis, Luigi, De Luca, Antonio, De Falco, Maria
Materialtyp: Artigo
Språk:Inglês
Publicerad: Hindawi Publishing Corporation 2014
Ämnen:
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC3920918/
https://ncbi.nlm.nih.gov/pubmed/24588001
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1155/2014/985478
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