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Modulation of Wolframin Expression in Human Placenta during Pregnancy: Comparison among Physiological and Pathological States

The WFS1 gene, encoding a transmembrane glycoprotein of the endoplasmic reticulum called wolframin, is mutated in Wolfram syndrome, an autosomal recessive disorder defined by the association of diabetes mellitus, optic atrophy, and further organ abnormalities. Disruption of the WFS1 gene in mice cau...

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Bibliographic Details
Main Authors: Lucariello, Angela, Perna, Angelica, Sellitto, Carmine, Baldi, Alfonso, Iannaccone, Alessandro, Cobellis, Luigi, De Luca, Antonio, De Falco, Maria
Format: Artigo
Language:Inglês
Published: Hindawi Publishing Corporation 2014
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3920918/
https://ncbi.nlm.nih.gov/pubmed/24588001
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1155/2014/985478
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