Modulation of Wolframin Expression in Human Placenta during Pregnancy: Comparison among Physiological and Pathological States

The WFS1 gene, encoding a transmembrane glycoprotein of the endoplasmic reticulum called wolframin, is mutated in Wolfram syndrome, an autosomal recessive disorder defined by the association of diabetes mellitus, optic atrophy, and further organ abnormalities. Disruption of the WFS1 gene in mice cau...

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Главные авторы: Lucariello, Angela, Perna, Angelica, Sellitto, Carmine, Baldi, Alfonso, Iannaccone, Alessandro, Cobellis, Luigi, De Luca, Antonio, De Falco, Maria
Формат: Artigo
Язык:Inglês
Опубликовано: Hindawi Publishing Corporation 2014
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Research Article
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC3920918/
https://ncbi.nlm.nih.gov/pubmed/24588001
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1155/2014/985478
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