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Role of the alpha-amino group of protein in ubiquitin-mediated protein breakdown.

Previous studies suggest that the conjugation of ubiquitin to NH2 groups of proteins is required for protein breakdown. We now show that the selective modification of NH2-terminal alpha-NH2 groups of globin and lysozyme prevents their degradation by the ubiquitin proteolytic system from reticulocyte...

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Détails bibliographiques
Auteurs principaux: Hershko, A, Heller, H, Eytan, E, Kaklij, G, Rose, I A
Format: Artigo
Langue:Inglês
Publié: 1984
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC392068/
https://ncbi.nlm.nih.gov/pubmed/6095265
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