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Role of the alpha-amino group of protein in ubiquitin-mediated protein breakdown.
Previous studies suggest that the conjugation of ubiquitin to NH2 groups of proteins is required for protein breakdown. We now show that the selective modification of NH2-terminal alpha-NH2 groups of globin and lysozyme prevents their degradation by the ubiquitin proteolytic system from reticulocyte...
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| Veröffentlicht in: | Proc Natl Acad Sci U S A |
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| Hauptverfasser: | , , , , |
| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
National Academy of Sciences
1984
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC392068/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/6095265/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.81.22.7021 |
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