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Role of the alpha-amino group of protein in ubiquitin-mediated protein breakdown.
Previous studies suggest that the conjugation of ubiquitin to NH2 groups of proteins is required for protein breakdown. We now show that the selective modification of NH2-terminal alpha-NH2 groups of globin and lysozyme prevents their degradation by the ubiquitin proteolytic system from reticulocyte...
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| Publié dans: | Proc Natl Acad Sci U S A |
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| Auteurs principaux: | , , , , |
| Format: | Artigo |
| Langue: | Inglês |
| Publié: |
National Academy of Sciences
1984
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| Sujets: | |
| Accès en ligne: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC392068/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/6095265/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.81.22.7021 |
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