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Müller glia cells regulate Notch signaling and retinal angiogenesis via the generation of 19,20-dihydroxydocosapentaenoic acid

Cytochrome P450 (CYP) epoxygenases generate bioactive lipid epoxides which can be further metabolized to supposedly less active diols by the soluble epoxide hydrolase (sEH). As the role of epoxides and diols in angiogenesis is unclear, we compared retinal vasculature development in wild-type and sEH...

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Hlavní autoři: Hu, Jiong, Popp, Rüdiger, Frömel, Timo, Ehling, Manuel, Awwad, Khader, Adams, Ralf H., Hammes, Hans-Peter, Fleming, Ingrid
Médium: Artigo
Jazyk:Inglês
Vydáno: The Rockefeller University Press 2014
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3920554/
https://ncbi.nlm.nih.gov/pubmed/24446488
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1084/jem.20131494
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