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Drosophila DNA topoisomerase I is associated with transcriptionally active regions of the genome.

The distribution of DNA topoisomerase I within Drosophila polytene chromosomes was observed by immunofluorescent staining with affinity-purified antibodies. The enzyme is preferentially associated with active loci, as shown by prominent staining of puffs. The heat shock loci 87A-87C are stained afte...

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Detalles Bibliográficos
Main Authors: Fleischmann, G, Pflugfelder, G, Steiner, E K, Javaherian, K, Howard, G C, Wang, J C, Elgin, S C
Formato: Artigo
Idioma:Inglês
Publicado: 1984
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC392055/
https://ncbi.nlm.nih.gov/pubmed/6095263
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