Elevated occipital β-amyloid deposition is associated with widespread cognitive impairment in logopenic progressive aphasia

BACKGROUND: Most subjects with logopenic primary progressive aphasia (lvPPA) have beta-amyloid (Aβ) deposition on Pittsburgh Compound B PET (PiB-PET), usually affecting prefrontal and temporoparietal cortices, with less occipital involvement. OBJECTIVES: To assess clinical and imaging features in lv...

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Main Authors: Whitwell, Jennifer L., Lowe, Val J., Duffy, Joseph R., Strand, Edythe A., Machulda, Mary M., Kantarci, Kejal, Wille, Samantha M., Senjem, Matthew L., Murphy, Matthew C., Gunter, Jeffrey L., Jack, Clifford R., Josephs, Keith A.
Formato: Artigo
Idioma:Inglês
Publicado em: 2013
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3920541/
https://ncbi.nlm.nih.gov/pubmed/23946416
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1136/jnnp-2013-305628
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