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Association study of the β-arrestin 2 gene (ARRB2) with opioid and cocaine dependence in a European American population

The rewarding properties of drugs of abuse are mediated by the Mu-Opioid Receptor (MOR). Genetic variation in MOR and MOR interacting proteins (MORIPs) involved in MOR signaling may increase risk for drug dependence. The MORIP, B-arrestin, plays an important role in the regulation of MOR trafficking...

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Main Authors: Ambrose-Lanci, Lisa M., Vaswani, Meera, Clarke, Toni-Kim, Zeng, Angela, Lohoff, Falk W., Ferraro, Thomas N., Berrettini, Wade H.
Format: Artigo
Sprog:Inglês
Udgivet: 2012
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3920286/
https://ncbi.nlm.nih.gov/pubmed/22472784
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1097/YPG.0b013e3283539528
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