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Antigen conformation determines processing requirements for T-cell activation.

We studied the difference in requirements for processing and presentation to a single T-cell clone of four different forms of the same epitope of sperm whale myoglobin--namely, on the native protein, on two conformationally altered forms of the protein, or as a 22-residue antigenic peptide fragment....

Cur síos iomlán

Sábháilte in:
Sonraí bibleagrafaíochta
Foilsithe in:Proc Natl Acad Sci U S A
Príomhchruthaitheoirí: Streicher, H Z, Berkower, I J, Busch, M, Gurd, F R, Berzofsky, J A
Formáid: Artigo
Teanga:Inglês
Foilsithe / Cruthaithe: National Academy of Sciences 1984
Ábhair:
Rochtain ar líne:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC392026/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/6333686/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.81.21.6831
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