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Effects of the Amino Acid Constituents of Microcystin Variants on Cytotoxicity to Primary Cultured Rat Hepatocytes

Microcystins, which are cyclic heptapeptides produced by some cyanobacterial species from algal blooms, strongly inhibit serine/threonine protein phosphatase and are known as hepatotoxins. Microcystins have many structural variations, yet insufficient information is available on the differences in t...

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Detalhes bibliográficos
Main Authors: Shimizu, Kumiko, Sano, Tomoharu, Kubota, Reiji, Kobayashi, Norihiro, Tahara, Maiko, Obama, Tomoko, Sugimoto, Naoki, Nishimura, Tetsuji, Ikarashi, Yoshiaki
Formato: Artigo
Idioma:Inglês
Publicado em: MDPI 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3920255/
https://ncbi.nlm.nih.gov/pubmed/24380975
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/toxins6010168
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