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Viral integration near c-myc in 10-20% of mcf 247-induced AKR lymphomas.

We induced AKR thymomas by injecting retrovirus MCF 247 that we had tagged with a fragment of phage lambda in its U3 region. About 10-20% of the 26 primary tumors studied showed both rearranged and germline c-myc bands in Southern blots. The rearranged c-myc genes were cloned from two of the tumors...

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Autores principales: Li, Y, Holland, C A, Hartley, J W, Hopkins, N
Formato: Artigo
Lenguaje:Inglês
Publicado: 1984
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC392021/
https://ncbi.nlm.nih.gov/pubmed/6093121
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