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Target polypeptide of a carcinogen is associated with normal mitosis and carcinogen-induced hyperplasias in adult hepatocytes.

Normal rat liver cytosol was found previously to contain a 14,000-dalton polypeptide that is the principal target of the carcinogen N-2-fluorenylacetamide (2-acetyl-aminofluorene) early during hepatocarcinogenesis. By using antiserum that identifies the 14,000-dalton polypeptide in liver cytosol, an...

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Argitaratua izan da:Proc Natl Acad Sci U S A
Egile Nagusiak: Custer, R P, Sorof, S
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: National Academy of Sciences 1984
Gaiak:
Sarrera elektronikoa:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC392006/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/6593726/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.81.21.6738
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