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Tolvaptan as a tool in renal physiology
For decades, the Brattleboro rat has been a useful model in kidney physiology. These animals manifest central diabetes insipidus (lack of circulating vasopressin) due to a mutation in the vasopressin-neurophysin gene. V2 receptor-mediated vasopressin actions in the kidney can be assessed in these an...
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Main Authors: | , , , |
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Formato: | Artigo |
Idioma: | Inglês |
Publicado em: |
American Physiological Society
2013
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Assuntos: | |
Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3920050/ https://ncbi.nlm.nih.gov/pubmed/24305472 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajprenal.00330.2013 |
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