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Global analysis of the effects of the V2 receptor antagonist satavaptan on protein phosphorylation in collecting duct

Satavaptan (SR121463) is a vasopressin V2 receptor antagonist that has been shown to improve hyponatremia in patients with cirrhosis, congestive heart failure, and syndrome of inappropriate antidiuresis. While known to inhibit adenylyl cyclase-mediated accumulation of intracellular cyclic AMP and po...

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Detalhes bibliográficos
Main Authors: Hoffert, Jason D., Pisitkun, Trairak, Saeed, Fahad, Wilson, Justin L., Knepper, Mark A.
Formato: Artigo
Idioma:Inglês
Publicado em: American Physiological Society 2013
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3920024/
https://ncbi.nlm.nih.gov/pubmed/24259510
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajprenal.00497.2013
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