Functional alteration of the beta-adrenergic receptor during desensitization of mammalian adenylate cyclase by beta-agonists.

Exposure of several mammalian cell lines to isoproterenol resulted in a desensitization of the beta-adrenergic receptor-adenylate cyclase system in membranes isolated from the cells. Under the experimental conditions chosen, desensitization was accompanied by a minimal loss of beta-receptors. The ce...

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Veröffentlicht in:	Proc Natl Acad Sci U S A
Hauptverfasser:	Kassis, S, Fishman, P H
Format:	Artigo
Sprache:	Inglês
Veröffentlicht:	National Academy of Sciences 1984
Schlagworte:	Research Article
Online-Zugang:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC391995/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/6093112/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.81.21.6686
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