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Effects of thyroxin and donepezil on hippocampal acetylcholine content and syntaxin-1 and munc-18 expression in adult rats with hypothyroidism

Adult-onset hypothyroidism induces various impairments in hippocampus-dependent cognitive function, in which numerous synaptic proteins and neurotransmitters are involved. Donepezil (DON), an acetylcholinesterase inhibitor, has been shown to be efficient in improving cognitive function. The aim of t...

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Detalhes bibliográficos
Main Authors: WANG, NAN, CAI, YAOJUN, WANG, FEN, ZENG, XIANZHONG, JIA, XUEMEI, TAO, FANGBIAO, ZHU, DEFA
Formato: Artigo
Idioma:Inglês
Publicado em: D.A. Spandidos 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3919934/
https://ncbi.nlm.nih.gov/pubmed/24520241
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3892/etm.2014.1487
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