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Novel Brain Arteriovenous Malformation Mouse Models for Type 1 Hereditary Hemorrhagic Telangiectasia

Endoglin (ENG) is a causative gene of type 1 hereditary hemorrhagic telangiectasia (HHT1). HHT1 patients have a higher prevalence of brain arteriovenous malformation (AVM) than the general population and patients with other HHT subtypes. The pathogenesis of brain AVM in HHT1 patients is currently un...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Choi, Eun-Jung, Chen, Wanqiu, Jun, Kristine, Arthur, Helen M., Young, William L., Su, Hua
Format: Artigo
Sprache:Inglês
Veröffentlicht: Public Library of Science 2014
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3919779/
https://ncbi.nlm.nih.gov/pubmed/24520391
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0088511
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