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Stimulatory GTP regulatory unit Ns and the catalytic unit of adenylate cyclase are tightly associated: mechanistic consequences.

Turkey erythrocyte membranes were solubilized in the mild detergent octylpenta(oxyethylene) [CH3(CH2)7-(OCH2CH2)5OH], which possesses a high critical micelle concentration (approximately equal to 6 mM) and forms small, dynamic micelles. Both the native enzyme Ns(GDP) X C and the p[NH]ppG-preactivate...

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Pubblicato in:Proc Natl Acad Sci U S A
Autori principali: Arad, H, Rosenbusch, J P, Levitzki, A
Natura: Artigo
Lingua:Inglês
Pubblicazione: National Academy of Sciences 1984
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Accesso online:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC391973/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/6436817/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.81.21.6579
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