Autism Associated Gene, ENGRAILED2, and Flanking Gene Levels Are Altered in Post-Mortem Cerebellum

BACKGROUND: Previous genetic studies demonstrated association between the transcription factor ENGRAILED2 (EN2) and Autism Spectrum Disorder (ASD). Subsequent molecular analysis determined that the EN2 ASD-associated haplotype (rs1861972-rs1861973 A-C) functions as a transcriptional activator to inc...

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Detalhes bibliográficos
Main Authors: Choi, Jiyeon, Ababon, Myka R., Soliman, Mai, Lin, Yong, Brzustowicz, Linda M., Matteson, Paul G., Millonig, James H.
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2014
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3919719/
https://ncbi.nlm.nih.gov/pubmed/24520327
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0087208
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