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A Large Solvent Isotope Effect on Protein Association Thermodynamics

Solvent reorganization can contribute significantly to the energetics of protein:protein interactions. However, our knowledge of the magnitude of the energetic contribution is limited, in part, by a dearth of quantitative experimental measurements. The biotin repressor forms a homodimer as a prerequ...

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Detalhes bibliográficos
Main Authors: Eginton, Christopher, Beckett, Dorothy
Formato: Artigo
Idioma:Inglês
Publicado em: 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3919658/
https://ncbi.nlm.nih.gov/pubmed/23984950
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/bi400952m
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