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Isolation of antiplasmodial anthraquinones from Kniphofia ensifolia, and synthesis and structure-activity relationships of related compounds

Bioassay-guided separation of the South African plant Kniphofia ensifolia for antiplasmodial activity led to the isolation of two new anthraquinones, named kniphofiones A and B (3, 4), together with three known bioactive anthraquinone monomers (1, 2 and 5), and four known bisanthraquinones (6–9). Th...

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Detalhes bibliográficos
Main Authors: Dai, Yumin, Harinantenaina, Liva, Bowman, Jessica D., Fonseca, Isabel Osorio Da, Brodie, Peggy J., Goetz, Michael, Cassera, Maria B., Kingston, David G. I.
Formato: Artigo
Idioma:Inglês
Publicado em: 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3919637/
https://ncbi.nlm.nih.gov/pubmed/24326280
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bmc.2013.11.032
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