Isolated rat hepatocyte couplets: a primary secretory unit for electrophysiologic studies of bile secretory function.
Hepatocyte couplets were isolated by collagenase perfusion from rat liver. Between adjacent cells, the bile canaliculus forms a closed space into which secretion occurs. As in intact liver, Mg2+-ATPase is localized at the canalicular lumen, the organic anion fluorescein is excreted, and secretion is...
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| Published in: | Proc Natl Acad Sci U S A |
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| Main Authors: | , , |
| Format: | Artigo |
| Language: | Inglês |
| Published: |
National Academy of Sciences
1984
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| Subjects: | |
| Online Access: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC391955/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/6149546/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.81.20.6516 |
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