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Synthesis and Characterization of an Antiapoptotic Immunosuppressive Compound for improving the Outcome of Islet Transplantation
Mycophenolic acid (MPA) is a commonly used immunosuppressive drug for human islet transplantation. However, it is toxic to transplanted islets, causing primary nonfunction. We recently synthesized a quinic acid derivative, 1,3,4,5-tetrahydroxy-N-propylcyclohexanecarboxamide (KZ41), which hold anti-i...
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| Auteurs principaux: | , , , , |
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| Format: | Artigo |
| Langue: | Inglês |
| Publié: |
2013
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| Sujets: | |
| Accès en ligne: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3919530/ https://ncbi.nlm.nih.gov/pubmed/24256337 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/bc400369t |
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