Antigen-specific helper T-cell clone supernatant is sufficient to induce both polyclonal proliferation and differentiation of small resting B lymphocytes.

Gradient-purified resting B lymphocytes can be polyclonally stimulated by antigen-specific major histocompatibility complex (MHC)-restricted helper T lymphocytes as well as by antigen-activated helper T-cell supernatant. In contrast to what has been described so far, we show that helper T-cell super...

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Udgivet i:Proc Natl Acad Sci U S A
Main Authors: Leclercq, L, Bismuth, G, Thèze, J
Format: Artigo
Sprog:Inglês
Udgivet: National Academy of Sciences 1984
Fag:
Research Article
Online adgang:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC391950/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/6238333/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.81.20.6491
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