Nitrendipine block of cardiac calcium channels: high-affinity binding to the inactivated state.
Block of Ca2+ currents by the dihydropyridine drug nitrendipine was studied in single canine ventricular cells by using the whole-cell variant of the patch clamp technique. When cells were held at depolarized membrane potentials at which Ca2+ currents were approximately equal to 70% inactivated, nit...
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| Udgivet i: | Proc Natl Acad Sci U S A |
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| Hovedforfatter: | |
| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
National Academy of Sciences
1984
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC391929/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/6093100/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.81.20.6388 |
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