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High-efficiency gene transfer into mammalian cells: generation of helper-free recombinant retrovirus with broad mammalian host range.

We have constructed a chimeric retrovirus genome containing ecotropic gag-pol sequences from Moloney murine leukemia virus and envelope sequences derived from the amphotropic virus 4070A. This reconstructed genome, termed pMAV-psi-, lacks the psi site required for encapsidation of the viral genome....

Ausführliche Beschreibung

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Bibliografische Detailangaben
Veröffentlicht in:Proc Natl Acad Sci U S A
Hauptverfasser: Cone, R D, Mulligan, R C
Format: Artigo
Sprache:Inglês
Veröffentlicht: National Academy of Sciences 1984
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Online-Zugang:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC391921/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/6093098/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.81.20.6349
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