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Characterisation and mechanisms of bradykinin-evoked pain in man using iontophoresis

Bradykinin (BK) is an inflammatory mediator that can evoke oedema and vasodilatation, and is a potent algogen signalling via the B1 and B2 G-protein coupled receptors. In naïve skin, BK is effective via constitutively expressed B2 receptors (B2R), while B1 receptors (B1R) are purported to be upregul...

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Detalhes bibliográficos
Main Authors: Paterson, Kathryn J., Zambreanu, Laura, Bennett, David L.H., McMahon, Stephen B.
Formato: Artigo
Idioma:Inglês
Publicado em: Lippincott Williams & Wilkins 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3919168/
https://ncbi.nlm.nih.gov/pubmed/23422725
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.pain.2013.01.003
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